la molecola cattiva
increasing levels in the brain prevents ROME
also impact was perhaps found a quick and easy way to help alcoholics stop drinking permanently. Sebastien Carnicella a researcher at the Gallo Research Center and colleagues found that increasing levels of a brain protein, GDNF, glial cell derived neurotrophic factor decreases the desire to drink immediately and also prevents the typical relapse in people who drank excessively .
The trial published in Proceedings of National Academy of Sciences (PNAS) has been done on laboratory mice who were injected in the brain area responsible for behavior that create alcohol dependence, growth factor and have seen that animals, after only 10 minutes after injection, showed no desire to drink more. Behavior that have maintained over time even when the wine has been made more available and after they were denied the rewards for two weeks.
Carnicella points out that this molecule does not inhibit the desire for other substances which provide pleasure, it had no adverse effects on the consumption of sugar by the mice. Furthermore, GDNF when injected not "rampant" in other areas of the brain, but remains active in the region in which it was made and this suggests that the molecule that is a natural growth factor of the organism has a specific and decisive role in block dependence. Given the chemical similarity of the molecular pathways between animals and humans, the researchers pensano che Gdnf possa diventare un candidato potenziale per trattare l’alcolismo nell’uomo